About the School PharmD Program Current Research Residency Program Current Research In the Community Alumni Society
John Alvin, PhD
photo of Alvin

Contact Information:

Office: 548 Salk Hall
Phone: 412-648-8572

jalvin@pitt.edu

Additional Information:

Associate Professor , Pharmaceutical Sciences

Following degrees from Central Catholic High School, Allegheny College in Meadville and University of Pittburgh School of Pharmacy, my doctorate in Pharmacology ensued under an NIH Pre-doctoral Fellowship. In 1971, I obtained an Andrew Mellon Career Development Award at Vanderbilt, training in esoteric analysis, synthesis and use of labeled drugs, tracking drugs in liver-impaired patients, and use of perfused liver and incubated liver cells to study drug metabolism and disposition. I obtained faculty status in 1973.

In 1975 I obtained Assistant Professorship at Pitt, with funding from the United Way, the American Heart Association and the NIH, studying labelled drugs in patients. In 1978-79, promoted to Associate Professor, I continued these studies to the present. Under a program for entrepreneurial academics at Pitt, I founded Pharmakon, an esoteric drug analysis/consulting firm, gaining 70 percent of the regional market and honored by the Wall Street Journal and NPR. For 25 years, as Director of a laboratory with Bureau of Laboratories and Clinical Laboratory Improvement Act certification, I conducted University research there employing instrumentation unavailable at Pitt, at no cost to Pitt, as did Pitt students, a testiment to the value of Pitt’s ‘academic entrepreneur’ program. Studies included drug micro-assay development, in vitro diagnostic procedures to guide drug therapy in fragile patients (neonates, transplant patients), and the effects of anti-seizure drugs on neonates, their clinical seizure patterns, EEGs, and physiology/toxicology, Work supported by NIH and foundations was published, notably, in New England Journal of Medicine, Pediatric Neorology, and Clinical Pharmacology, and honored in the 2001-02 Yearbook of American Society of Pediatrics. In 2005, this work was integrated into Pitt as the Analytical Laboratory for Translational and Clinical Studies, also legally certified under my direction. It is one of the few, if not singular, facilities nationally formally associated with a University.