Bio:
Sandra L. Kane-Gill, Pharm.D., M.S., FCCM, FCCP, is Associate Professor of Pharmacy and Therapeutics at the University of Pittsburgh School of Pharmacy in Pittsburgh, Pennsylvania. She also serves as Associate Professor for the Center for Pharmacoinformatics and Outcomes Research at the School of Pharmacy. She has secondary appointments in the School of Medicine in the Clinical Translational Science Institute, Deparment of Critical Care Medicine and the Department of Biomedical Informatics. In addition to her academic appointments, Dr. Kane-Gill is Critical Care Medication Safety Officer at the University of Pittsburgh Medical Center in the Department of Pharmacy.
Dr. Kane-Gill received her Bachelor of Science degree in pharmacy from Wayne State University in Detroit, Michigan. She completed a pharmacy practice residency accredited by the American Society of Health-System Pharmacists at West Virginia University Hospital in Morgantown, West Virginia, and earned a Doctorate of Pharmacy degree from the University of Toledo in Toledo, Ohio. Dr. Kane-Gill then pursued her Master of Science degree in Pharmacy Administration with emphasis on Pharmacoeconomics and Health Outcomes at The Ohio State University in Columbus, Ohio and she completed a critical care fellowship at The Ohio State University.
Dr. Kane-Gill’s interests focus on health service research, including the assessment of economic, clinical, and quality outcomes for critically ill patients. Her goal is to identify effective approaches for the detection, prevention, and management of medication errors and adverse drug events as to improve quality of care and patient safety. Dr. Kane-Gill has served as Principal Investigator and Co-Investigator on several funded research grants in this area of study. Her work has been presented at several professional meetings, and she has published more than 80 articles and book chapters related to critical care and patient safety. Her endeavors include editing recently published books on the use of high-risk intravenous medications in special patient populations and drug induced complications in critically ill patients. She is on the editorial board for Critical Care Medicine and the Annals of Pharmacotherapy.
Dr. Kane-Gill is an active member of the American College of Clinical Pharmacy (ACCP), Society of Critical Care Medicine (SCCM), and International Society for Pharmacoeconomics and Outcomes Research. At the 2011 Annual Meeting of ACCP, Dr. Kane-Gill received the Critical Care Practice and Research Network (PRN) Research Award. At the 2012 SCCM meeting she was recognized for her contributions in medication safety error prevention with the Clinical Pharmacy and Pharmacology Section Technology Patient Safety Award. She is a fellow in the American College of Critical Care Medicine and ACCP.
Research Interest
Dr. Kane-Gill’s interests focus on health service research including the assessment of economic, clinical and quality outcomes. Her goal is to identify effective approaches for the detection, prevention and management of medication errors and adverse drug events to improve quality of care and promote patient safety. She has led several pharmacopidemiology evaluations that improved patient safety surveillance systems, prevented medication errors and adverse drug events, used patient reported outcomes to improve quality of care, used information technology to improve services and developed models of cost for acute illness. To ensure the optimal quality of care for patients she has also completed several comparative effectiveness trials that analyze the safe use of high-risk drugs such as anticoagulants. Several of the pharmacoepidemiology studies she has completed used large administrative databases to accomplish the study endpoints with the largest including 20 million patients. She has served as Principal Investigator and Co-Investigator on several funded research grants in this area of study. Her work has been presented at several national and international professional meetings.
Publications
Kane-Gill SL, Forsberg EA, Verrico MM, Handler SM.Comparison of three pharmacovigilance algorighms in the ICU setting: a retrospective and prospective evaluation of ADRs. Drug Saf 2012;35:645-53.
Harinstein LM, Kane-Gill SL, Smithburger PL, Culley CM, Reddy VK, Seybert AL. Use of a laboratory-drug combination alert to detect drug-induced thrombocytopenia in critically ill patients. J Crit Care 2012;27:242-249.
Kane-Gill SL, Cagle WE, Stockwell D. Active patient safety surveillance systems used to prevent ADEs in the ICU. In: Papadopoulos J, Cooper B, Kane-Gill SL, Mallow-Corbett S, Barletta J.(editors) Drug induced complications in critically ill patients: a guide for recognition and treatment. 2012:347-358.
Kane-Gill SL, Jacobi J, Rothschild JR. Adverse drug events in the ICU: risk factors, impact and role of team care. Crit Care Med 2010;suppl:s83-89
Stockwell D and Kane-Gill SL. Developing a patient safety surveillance system to prevent adverse drug events in the ICU. Crit Care Med 2010;(suppl):s117-25.
Kane-Gill SL, Van Den Bos J, Handler SM. A comparison of adverse drug reactions in ambulatory care and hospital settings using a large database. Ann Pharmacother 2010;44:1054-1060.
Ford DG, Seybert AL, Smithburger PL, Kobulinsky L, Samosky J, Kane-Gill SL. Impact of simulation-based learning on medication error rates in critically ill patients. Intens Care Med 2010;36:1526-1531.
Kane-Gill SL and Buckley MS. In: Richardson M, Chant C, Cheng JWM, Chessman KH, Hemstreet Hume AL, BA e, et al, eds. Pharmacotherapy Self-Assessment Program (PSAP), 7th ed. Safe Drug Use in the Critically Ill Patients. Lenexa, KS: American College of Clinical Pharmacy, 2010:145-159.
Kane-Gill SL, Kowiatek JG, Weber RJ. A comparison of voluntarily reported medication errors in intensive care and general care units. Qual Saf Health Care. 2010; 19:55-59.
Dasta JF, Kane-Gill SL, Pencina M, Shehabi, Y, Bokesch P, Riker R. A cost-minimization analysis of dexmedetomidine compared to midazolam for long-term sedation in the intensive care unit. Crit Care Med, 2010;38(2): 497-503.
Kane-Gill SL, Bellamy CJ, Verrico MM, Saul MI, Handler SM, Weber RJ. Evaluating the positive predictive values of antidote signals to detect potential adverse drug reactions (ADRs) in the medical intensive care unit (ICU). Pharmacoepidemiol Drug Saf 2009;18:1185-1191.
Kane-Gill SL, Seybert AL, Lazar J, Shatzer M, Saul MI, Kirisci L, Murali S. Resource use in decompensated heart failure by disease progression category. Congest Heart Fail 2007;13:22-28.
Kane-Gill SL, Rea RS, Verrico P, Weber RJ. ADE rates for high cost and frequently used drugs in the ICU: Redirecting pharmacist’s time toward ADE prevention efforts. Am J Health Syst Pharm 2006;63:1876-1881.
Kane-Gill SL, Devlin JW. Adverse drug event reporting in the intensive care unit: a survey of current practices. Ann Pharmacother 2006;40:1267-1273.
Kane-Gill SL, Dasta JF, Schneider PJ, Cook CH. Monitoring abnormal laboratory values as antecedents to drug induced injury. J Trauma 2005; 59:1457-1462.
Kane-Gill SL, Kirisci L, Pathak DS. Are the Naranjo criteria reliable and valid for determination of adverse drug reactions in the intensive care unit? Ann Pharmacother 2005; 39: 1823-1827.
Presentations
Recent Presentations
Evaluating New Pharmaceutical Products at Your Health System - Efficacy, Safety and Economic Considerations in Developing Medication-use Evaluations
Presented at the 45th ASHP Midyear Clinical Meeting, Las Vegas, NV
Assessing and Managing Sedation – Incorporating the PAD Guidelines into Practice
Presented at the Downstate New York Society of Health System Pharmacists, New York, NY.
Establishing a Safety Culture in the ICU: Making Systematic Changes Using ADE Data
Presented at the 41st SCCM Critical Care Congress, Houston, Tx
Strategies for Improving the Safe Use of IV Medications in the Critical Care Setting.
Presented at the 44th ASHP Midyear Clinical Meeting, New Orleans, LA
Economic Implications of Postoperative Pain Management
Presented at the 44th ASHP Midyear Clinical Meeting, New Orleans, LA
The Great Masquerader: Recognizing ADRs in the ICU Learning Using Simulation
Presented at the ACCP 2011 Annual Meeting, Pittsburgh, PA.
Severity and Preventability of Drug-Induced Hypotension
Presented at the ACCP 2011 Annual Meeting, Pittsburgh, PA.
