Office: 3SCR6.4610-7, 1881 East Road, Houston Texas 77054

Phone: 713-486-5482

Email: hac40@pitt.edu

Program: PhD
Track: Medicinal Chemistry
Advisor: Xiang-Qun (Sean) Xie, PhD, EMBA

EDUCATION

School of Pharmacy, University of Pittsburgh, Pittsburgh, US
➢ PhD Student: 2013 – Present
➢ Core Courses: Statistics, Pharmaceutical Sciences Seminar, Pharmacology and Therapeutics, Teach Me to Teach You, Journal Club, Pharmaceutical Analysis, Foundations of Pharmaceutical Science, Grant Writing, Advanced Topics in Gene Expression

School of Medicine, Soochow University, Suzhou, China
➢ Medical Degree: Doctor of Medicine, 2002 – 2007
➢ Core Courses: Higher Mathematics, Inorganic Chemistry, Organic Chemistry, Medical Physics, Anatomy, Histology and Embryology, Physiology, Biochemistry, Pathology, Pharmacology, Medicine, Surgery, Radiation Therapy
➢ Advanced courses: Radiation Chemistry, Radiation Physics, Radiation Dosimetry, Radiation Protection, Radiation Biology, Radiation Oncology, Radiotoxicology
➢ Summer programs:
a) Second Military Medical University, Shanghai, China, 2005
b) Institute of Hematology of Peking Union Medical College, Tianjin, China, 2007
➢ Internship: Jinling Hospital, Nanjing, China, 2007
Departments of Respiratory, Digestion, Cardiology, General Surgery, Radiotherapy

Residency

Radiation Therapy Center, Changhai Hospital, Shanghai, China --- 8.2007 – 1.2009
➢ Performed 3DCRT(3-dimensional conformal radiation therapy) and IMRT(Intensity-modulated radiation therapy)

Research Experience

Ph.D. off-campus research at University of Texas Health Science Center at Houston --- 9.2015 - present

➢ Muscle-derived Stem Cell mutipotential of differention during nature aging process

School of Pharmacy, University of Pittsburgh --- 9. 2014 – 6. 2015
➢ PhD student lab rotation
a) Involved in a project on small molecules screening for stem cells self-renew
b) Joined in constructing a chemogenomics knowledge base of stem cells signaling
c) Validated hematopoietic stem cells self-renew signaling database with known target compounds by performing HTDocking
d) Validated in-house compounds’ inhibitory effect between p18( INK4 family cyclin-dependent kinase inhibitor ) and CDK6 ( cyclin dependent kinase ) by designing and performing radioactive isotope kinase activity assay

Department of Radiation Oncology, University of Pittsburgh Cancer Institute --- 1. 2009 – 12. 2012
➢ Prof. Tao Cheng’s Lab
a) Mainly worked on a project named “negative effects of irradiated hosts on transplanted Hematopoietic Stem Cells” aiming to quantify the negative effects, the mechanisms, and improvement of HSC engraftment by manipulating irradiated host microenvironment
b) Further evaluated other anti-oxidative agents such as MnSOD in protecting HSCs in the irradiated hosts
c) Designed and conducted experiments to investigate Role of Nrf2 in hematopoiesis radiation protection

Research Skills

➢ Animal work: Breed and Genotype; Isolate Mouse’s Bone Marrow; Mouse Tail Vein Injection; Mouse Peritoneal Injection
➢ Molecular Biology: PCR; DNA extraction; Gel Electrophoresis; Primer Design; RNA Isolation; RT-PCR; Bacterial Transformation; Western Blotting
➢ Stem Cell Biology: Transfection; Cell Culture; Immunostaining; Flow Cytometry; single cell transplant

Conferences

➢ Tianjin International Stem Cell Conference --- 11. 2010
Attended the course of stem cell theory and experimental technology
➢ McGowan Institute for Regeneration Medicine Annual Retreat --- 3. 2011
➢ 53rd Annual Meeting and Exposition for American Society of Hematology --- 12. 2011
➢ NIDDK sponsored workshop on hematopoietic stem cell self-renewal, lineage commitment and terminal differentiation --- 2. 2012