The Center for Pharmacogenetics is proud to announce that Dr. Yong Tae Kwon has been awarded a NIH R01 grant entitled “Role of Ubiquitin in Cardiovascular System.” The grant is funded by the National Heart, Lung, and Blood Institute (NHLBI) for the period of 07/15/06 to 05/31/2011.

The Center for Pharmacogenetics is proud to announce that Dr. Haibiao Gong has been promoted to the rank of Research Assistant Professor effective July 1, 2006.

The Center for Pharmacogenetics is proud to announce that Dr. Song Li has been promoted to Associate Professor of Pharmaceutical Sciences with tenure, effective June 1, 2006.

The Center for Pharmacogenetics is pleased to announce that the following manuscript by Jie Zhou from Dr. Wen Xie's lab has been accepted for publication in the Journal of Biological Chemistry on March 23, 2006.
Jie Zhou, Yonggong Zhai, Ying Mu, Haibiao Gong, Hirdesh Uppal, David Toma, Songrong Ren, Ronald M Evans, and Wen Xie. A novel PXR-mediated and SREBP-independent lipogenic pathway.

The Center for Pharmacogenetics is pleased to announce that the following manuscript first authored by Jee Young An from Dr. Yong Tae Kwon's lab has been accepted for publication in the Proceedings of the National Academy of Sciences of the United States of America.
An, J.Y., J.W. Seo, T. Tasaki, M.J. Lee, A. Varshavsky, and Y.T. Kwon.(2006) Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Proc. Natl. Acad. Sci. USA (in press).

The Center for Pharmacogenetics is proud to announce that Dr. Yong Tae Kwon has been awarded a grant entitled “Proteomics of Ubiquitin-Dependent N-End Rule Pathway.” The grant is funded by the National Institutes of Health, National Institute of General Medical Sciences for the period of 02/1/06 to 01/31/2010.

The Center for Pharmacogenetics is proud to announce that Dr. Takafumi Tasaki has been promoted to the rank of research assistant professor as of September 1, 2005.

The Center for Pharmacogenetics is proud to announce that Dr. Ying Mu has been awarded a Keystone Symposia scholarship/travel award for up to $1000 to attend the upcoming meeting on Nuclear Receptors: Orphan Brothers in March of 2006. The award is funded by a National Institutes of Health, National Institute of Diabetes, Digestive and Kidney Disease Grant.

The Center for Pharmacogenetics is happy to announce that the following manuscript by Ying Mu from Dr. Wen Xie's lab has been accepted for publication in the Journal of Pharmacology and Experimental Therapeutics.
Mu Y, Zhang J, Zhang S, Toma D, Ren S, Huang L, Yaramus M, Baum A, Venkataramanan R, and Xie W. Traditional Chinese Medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) Activate PXR and Increase Warfarin Clearance in Rats.

The Center for Pharmacogenetics is happy to announce that the following manuscript by Fengtian He and Jiang Li (co-1st authors) from Dr. Song Li’s lab has been accepted for publication in Circulation Research.
Fengtian He, Jiang Li, Ying Mu, Ramalinga Kuruba, Zheng Ma, Annette Wilson, Sean Alber, Yu Jiang, Troy Stevens, Simon Watkins, Bruce Pitt, Wen Xie, and Song Li.  "Downregulation of Endothelin-1 by Farnesoid X Receptor in Vascular Endothelial Cells."