Directory Profile

Program: PhD
Track: Pharmacometrics and Systems Pharmacology
Advisor: Zhiwei Feng, PhD

Graduated from Jiangnan University. Now work in University of Pittsburgh school of Pharmacy Dr Xie lab. Research mainly falls under the field of computer-aided drug design with a focus on (1) homology modeling of antibody three-dimensional structure, (2) Identification of key residues that contribute to the antibody-antigen binding and in-silico prediction of the conformation of antibody-antigen complex (e.g. Antibody-antigen docking, MD simulation, etc.), (3) construction of antibody database to facilitate the development of antibody.

Focus on antibody engineering and vaccine design. For example: (1) homology modeling of antibody three-dimensional structure, (2) Identification of key residues that contribute to the antibody-antigen binding and in-silico prediction of the conformation of antibody-antigen complex (e.g. Antibody-antigen docking, MD simulation, etc.), (3) construction of antibody database to facilitate the development of antibody.