Past Students

Alexander Prokopienko, PhD

• PhD, 2020
• Dissertation/Thesis: Effect of Kidney Disease and Gut-Derived Uremic Toxins on Flavin Monooxygenases: Clinical and Translational Research Studies
• Advisor: Thomas D. Nolin, PharmD, PhD

Rujuta Joshi, PhD

• PhD, 2018
• Dissertation/Thesis: Optimization of Mycophenolate Mofetil Dosing in Transplantation
• Advisor: Raman Venkataramanan, PhD

Solomon Adams, PharmD, PhD

• PhD, 2018
• Dissertation/Thesis: Targeting the Genetic and Molecular Role of ABSG2 Following Severe Traumatic Brain Injury
• Advisor: Philip E. Empey, PharmD, PhD

Hari Kalluri, PharmD PhD

• PhD, 2018
• Dissertation/Thesis: Characterization of Renal Secretion in Renal Transplant Patients
• Advisor: Raman Venkataramanan, PhD

Omar Almazroo, PhD

• PhD, 2017
• Dissertation/Thesis: PRECLINICAL AND CLINICAL EVALUATION OF TREPROSTINIL IN MINIMIZING HEPATIC ISCHEMIA AND REPERFUSION INJURY
• Advisor: Raman Venkataramanan, PhD

Kacey Anderson, PhD

• PhD, 2017
• Dissertation/Thesis: The Effect of Therapeutic Hypothermia on Drug Metabolism and Transport: Clinical and Pre-Clinical Investigations
• Advisor: Samuel M. Poloyac, PharmD, PhD

Brian Kiesel, MS

• MS, 2016
• Dissertation/Thesis: The Toxicology, Pharmacokinetics and Metabolism of a Novel IL-6 Induced STAT3 Inhibitor.
• Advisor: Jan Beumer, PharmD, PhD

Chenxiao Tang, MS

• MS, 2017
• Dissertation/Thesis: SCREENING 20-HETE INHIBITORS IN MICROSOMAL INCUBATES USING UPLC-MS/MS
• Advisor: Thomas D. Nolin, PharmD, PhD

Dustin Walsh, MS

• MS, 2016
• Dissertation/Thesis: DRUG TRANSPORTERS AND NHERF PDZ PROTEINS
• Advisor: Thomas D. Nolin, PharmD, PhD

Shoroq Altawalbeh, Phd

• Phd, 2016
• Dissertation/Thesis: ADDITION OF LEUKOTRIENE RECEPTOR ANTAGONISTS VERSUS LONG ACTING BETA AGONISTS TO INHALED CORTICOSTEROID THERAPY FOR ASTHMA TREATMENT IN OLDER ADULTS: A RETROSPECTIVE DATA ANALYSIS OF EFFECTIVENESS, SAFETY AND COST
• Advisor: Joshua Thorpe, PhD, MPH

Tiantian Gong, PhD

• PhD, 2016
• Dissertation/Thesis: VAGINAL DELIVERY OF A HYDROPHOBIC ANTIRETROVIRAL DRUG CSIC FOR HIV PREVENTION: NOVEL FORMULATION STRATEGIES FOR IMPROVED DRUG SOLUBILIZATION AND LYMPHATIC TARGETING
• Advisor: Lisa C. Rohan, PhD

Ali Alshabi, PhD

• PhD, 2016
• Dissertation/Thesis: REGULATION OF PHASE I, II, AND III PATHWAYS BY PREGNANCY RELATED HORMONES
• Advisor: Raman Venkataramanan, PhD

Lindsay Ferguson Kramzer, PharmD, PhD

• PhD, 2015
• Dissertation/Thesis: Preformulation and Biological Evaluations for the Intravaginal Delivery of Griffithsin for HIV Prevention
• Advisor: Lisa C. Rohan, PhD

Lingjue Li, MS

• MS, 2015
• Dissertation/Thesis: Effect of Ovariectomy, Estrogen and Cholinergic Input on Aromatase in Different Brain Regions
• Advisor: Samuel M. Poloyac, PharmD, PhD

Osama Alshogran, PhD

• PhD, 2015
• Dissertation/Thesis: Characterization of the Effect of Chronic Kidney Disease on Hepatic Drug Reduction: In-Vitro and In-Vivo Studies of Warfarin
• Advisor: Thomas D. Nolin, PharmD, PhD

Ellen Press, MS

• MS, 2015
• Dissertation/Thesis: Biofilm Production and Susceptibility Among Candida Albicans Isolates from Various Clinical Sites
• Advisor: Samuel M. Poloyac, PharmD, PhD

Mohammad Shawaqfeh, PhD

• PhD, 2014
• Dissertation/Thesis: Potential Contributors to the Decreased Vitamin B6 Levels After Transplantation
• Advisor: Raman Venkataramanan, PhD

Robert Parise, PhD

• PhD, 2014
• Dissertation/Thesis: The Preclinical and Clinical Pharmacology of Benzaldehyde Dimethane Sulfonate (BEN) for the Treatment of Renal Cell Carcinoma
• Advisor: Raman Venkataramanan, PhD
• Co-advisor: Jan Beumer, PharmD, PhD

Danfeng Shen, MS

• MS, 2014
• Advisor: Maggie Folan, PhD

Jennifer Bonner, PhD

• PhD, 2012
• Dissertation/Thesis: Intestinal drug absorption, cytochrome P450-mediated metabolism, and transport after small bowel transplantation.
• Advisor: Raman Venkataramanan PhD

Jeremiah Momper, PharmD, PhD

• PhD, 2011
• Dissertation/Thesis: Characterization of Renal Anionic Drug Transport Capacity in Kidney Transplant Recipients with Persistent BK Viremia: Pharmacokinetic and Pharmacodynamic Studies of Cidofovir
• Advisor: Raman Venkataramanan, PhD

Nisanne Ghonem, PharmD, PhD

• PhD, 2010
• Dissertation/Thesis: Treprostinil For Protection Of Liver Grafts Against Ischemia And Reperfusion Injury During Orthotopic Liver Transplantation - A Translational Study
• Advisor: Raman Venkataramanan, PhD

Yuyan Jin, PhD

• PhD, 2010
• Dissertation/Thesis: Quantifying Variability In Drug Disposition, Response And Public Health Outcomes: The Implementation Of Pharmacometric Based Modeling And Simulation Approaches
• Advisor: Robert R. Bies, PharmD, PhD

Shringi Sharma, PhD

• PhD, 2009
• Dissertation/Thesis: Pre-Clinical And Clinical Pharmacology Of 17alpha-Hydroxyprogesterone Caproate (17-Ohpc): An Agent For The Prevention Of Preterm Birth.
• Advisor: Raman Venkataramanan, PhD

Marci Chew, PhD

• PhD, 2007
• Dissertation/Thesis: Anticholinergic Medications And Cognition In Older Adults
• Advisor: Bruce Pollock, MD, PhD

Kristin Bigos, PhD

• PhD, 2007
• Dissertation/Thesis: Pharmacodynamics Of IV Citalopram Using Functional MRI
• Advisor: Robert R. Bies, PharmD, PhD
• Awards
• Presentations
• Publications

Michael Tortorici, PharmD, PhD

• PhD, 2007
• Dissertation/Thesis: The Effects Of Therapeutic Hypothermia On Cytochrome P450-Mediated Metabolism: Studies In Translational Research
• Advisor: Samuel Poloyac, PharmD, PhD

Yan (Summer) Feng, PhD

• PhD, 2006
• Dissertation/Thesis: Modeling And Simulation Approach To Characterize The Magnitude And Consistency Of Drug Exposure Using Sparse Concentration Sampling
• Advisor: Robert R. Bies, PharmD, PhD

Aarati Ranade, PhD

• PhD, 2005
• Dissertation/Thesis: The Effect Of Endogenous And Exogenous Chemicals On Drug Metabolizing Enzymes And Drug Transporters In Human Hepatocytes
• Advisor: Raman Venkataramanan, PhD

Rama Sivasubramanian, PhD

• PhD, 2005
• Dissertation/Thesis: Effect Of Valerian Root Extracts (Valeriana Officinalis) On Acetaminophen Glucuronidation: In Vitro And In Vivo Studies
• Advisor: Raman Venkataramanan, PhD

William Zamboni, PharmD, PhD

• PhD, 2005
• Dissertation/Thesis: Preclinical And Clinical Pharmacologic Studies Of 9-Nitrocamptothecin And Its 9-Aminocamptothecin Metabolite
• Advisor: Merril Egorin, MD

Bernard Komoroski, PharmD, PhD

• PhD, 2005
• Dissertation/Thesis: The Direct And Indirect Effects Of Herbal Products On Common Drug Metabolizing Enzymes And Drug Transporters
• Advisor: Raman Venkataramanan, PhD

Matthew Hruska, PharmD, PhD

• PhD, 2004
• Dissertation/Thesis: Characterization Of Cytochrome P450 2c8 Activity In Vivo: Pharmacogenetic And Pharmacokinetic Studies Of Rosiglitazone Metabolism
• Advisor: Reginald F. Frye, PharmD, PhD

Maggie Folan, BSN, PhD

• PhD, 2003
• Dissertation/Thesis: Impact Of Dhea On Gaba-Agonist Challenge In Healthy Young And Older Adults
• Advisor: Patricia D. Kroboth, PhD

Thomas Nolin, PharmD, PhD

• PhD, 2003
• Dissertation/Thesis: Characterization Of The Effect Of Chronic Kidney Disease On Cytochrome P450 Activity In Humans
• Advisor: Reginald F. Frye, PharmD, PhD

Tanya Fabian, PharmD, PhD

• PhD, 2003
• Dissertation/Thesis: Stress Associated With Implanted Defibrillators: Evaluation Of Psychological, Pharmacological, And Neurohormonal Response
• Advisor: Patricia D. Kroboth, PhD

Khalid Al-Kharfy, PharmD, PhD

• PhD, 2002
• Dissertation/Thesis: Characterization Of Ugt Activity In Vitro And In Vivo: Modulation By Genetic And Non-Genetic Factors
• Advisor: Reginald F. Frye, PharmD, PhD

Abdullah Mohizea, PhD

• PhD, 2002
• Dissertation/Thesis: Drug Metabolism And Transport During Rejection Of Transplanted Liver
• Advisor: Raman Venkataramanan, PhD

Jang Lee, PharmD, PhD

• PhD, 2000
• Dissertation/Thesis: Application Of The Semi-Simultaneous Bioavailability Approach To Hepatic And Intestinal Cyp3a Phenotyping With Midazolam
• Advisor: Reginald F. Frye, PharmD, PhD

Kenneth Bauer, PharmD, PhD

• PhD, 1999
• Dissertation/Thesis: The Molecular And Clinical Pharmacology Of Carboxyamido-Triazole, And A Clinical Trial In Prostate Cancer
• Advisor: Rowena Schwartz, PharmD

Thomas Dowling, PharmD, PhD

• PhD, 1999
• Dissertation/Thesis: Novel Approaches To Characterizing In Vivo Glomerular And Tubular Functional Capacity
• Advisor: Gary R. Matzke, PharmD

Firoozeh Salek, PharmD, PhD

• PhD, 1999
• Dissertation/Thesis: Alprazolam And Dhea In Healthy Men And Women
• Advisor: Patricia D. Kroboth, PhD

Arun Swaminathan, PhD

• PhD, 1997
• Dissertation/Thesis: Intestinal Absorption Of Immunosuppressive Drugs Cyclosporine And Tacrolimus
• Advisor: Raman Venkataramanan, PhD

Rae Ann Maxwell, BS, RPh, PhD

• PhD, 1997
• Dissertation/Thesis: A Dose Response Evaluation Of The Effects Of Alprazolam And Buspirone On The P300 - A Measure Of Cognition
• Advisor: Patricia D. Kroboth, PhD

Amy Pittenger, PharmD, MS

• MS, 1996
• Dissertation/Thesis: Correlation Of Dehyroepiandrosterone, Dehydroepiandrosterone-Sulfate And Cortisol Concentrations To Acute Physiology And Chronic Health Evaluation Ii Score
• Advisor: Patricia D. Kroboth, PhD

Richard Bertz, PhD

• PhD, 1995
• Dissertation/Thesis: Sensitivity And Rate Of Tolerance Development To Benzodiazepines : Clinical Studies Of Aging And In Vitro Study With Neurosteroids
• Advisor: Patricia D. Kroboth, PhD

Reginald Frye, PharmD, PhD

• PhD, 1995
• Dissertation/Thesis: Characterization Of In Vivo Drug Metabolizing Activities: Validation Of Chlorzoxazone As A Probe Of Cyp2e1 And A Cocktail To Assess Multiple Enzymes
• Advisor: Gary R. Matzke, PharmD

Richard Lush, PhD

• PhD, 1994
• Dissertation/Thesis: Modulation Of Etoposide Cytotoxicity By Recombinant Human Tumor Necrosis Factor And Other Agents: Laboratory Investigations And A Phase I Clinical Study
• Advisor: Rowena Schwartz, PhD

James McAuley, PhD

• PhD, 1993
• Dissertation/Thesis: Neurosteroids And The Gaba-Benzodiazepine Receptor Complex: Receptor Binding And Clinical Implications
• Advisor: Patricia D. Kroboth, PhD

Karen Habucky, PhD

• PhD, 1992
• Dissertation/Thesis: Fk506: Its Pharmacokinetics And Interaction With Other Drugs
• Advisor: Raman Venkataramanan, PhD

Chris Derry, PhD

• PhD, 1991
• Dissertation/Thesis: Pharmacokinetics And Pharmacodynamics Of Intravenous Triazolam In Normal And Obese Men
• Advisor: Patricia D. Kroboth, PhD

Virginia Schmith, PhD

• PhD, 1989
• Dissertation/Thesis: Sensitivity Of Dialysis Patients To Alprazolam : Single Dose Pharmacokinetics And Pharmacodynamics
• Advisor: Patricia D. Kroboth, PhD

Iman Zaghloul, PhD

• PhD, 1987
• Dissertation/Thesis: Factors Effecting Cyclosporine Pharmacokinetics
• Advisor: Raman Venkataramanan, PhD

May Lynn Huang, PhD

• PhD, 1987
• Dissertation/Thesis: Drug Disposition In Liver Transplant Patients And Immunsuppresive Drug Interaction In Rabbits
• Advisor: Raman Venkataramanan, PhD

Pamela Garzone, PhD

• PhD, 1987
• Dissertation/Thesis: Stable Isotope Technology In Drug-Drug Interactions : The Effects Of Cimetidine, Ranitidine And Antacid On The Pharmacokinetics Of Midazolam
• Advisor: Patricia D. Kroboth, PhD

Patricia Kroboth, PhD

• PhD, 1983
• Dissertation/Thesis: Pharmacokinetics And Pharmacodynamics Of Triazolam And Temazepam In Dialysis Patients And The Effect Of Aluminum Hydroxide On Absorption Of These Agents
• Advisor: Randy P. Juhl, PhD