I am a PhD student at the University of Pittsburgh, School of Pharmacy, in the laboratory of Dr. Simone Brixius-Anderko. I received my undergraduate degree in bioengineering from Northeastern University in China (NEU, China) and my Master’s degree in pharmaceutical sciences from the University of Southern California (USC). My current research focuses on the role of the cytochrome P450 4F11 (CYP4F11) in the development of non-small cell lung cancer (NSCLC) development. During my PhD training, I have gained experience in recombinant protein expression, purification, X-ray crystallization, and I am currently learning HPLC and mass spectrometry techniques for metabolomics.
Graduate Track Affiliation(s)
Biochemical Pharmacology
Graduate Program Affiliation(s)
PhD in Pharmaceutical Sciences: Biochemical Pharmacology
Practice Area/Expertise
Cell biology, recombinant protein expression, purification, X-ray crystallization, HPLC, mass spectrometry
Research / Project
CYP4F11 in non-small cell lung cancer development
Honors / Awards
• Pitt Graduate Program Travel Award 04/2025 • Pharmaceutical Sciences Research Symposium (PSRS) Best podium presentation award 02/2025 • 81st Pittsburgh Diffraction Conference (PDB) Travel award in Ithaca, NY 09/2024 • Drug Metabolism and Disposition Highlighted Trainee Author of the American Society for Pharmacology and Experimental Therapeutics (ASPET) 02/2024 • ASPET Travel Award for ASPET Annual Meeting in Arlington, VA 04/2024
Recent Publications
1. On the interface of fatty acid metabolism: A crosstalk between fatty acid omega-hydroxylase CYP4F11 and fatty acid desaturase 2 in non-small cell lung cancer, H. Jia and S. Brixius-Anderko, Drug Metab Dispos 2025 Vol. 54 Issue 1 Pages 100221; 2. The curious family of cytochrome P450 4F fatty acid omega-hydroxylases: recent developments in their function and relevance for human health, B. C. Alves Chagas, H. Jia, B. Brixius and S. Brixius-Anderko, Open Biol 2025 Vol. 15 Issue 8 Pages 250115; 3. Deciphering the Role of Fatty Acid-Metabolizing CYP4F11 in Lung Cancer and Its Potential As a Drug Target, H. Jia, B. Brixius, C. Bocianoski, S. Ray, D. R. Koes and S. Brixius-Anderko, Drug Metab Dispos 2024 Vol. 52 Issue 2 Pages 69-79.
Presentations
• Huiting Jia, Simone Brixius-Anderko. A crosstalk between FADS2 and CYP4F11 in NSCLC on the interface of fatty acid metabolism. Oral presentation at the virtual P450 Meeting (Trainee session), Sep 2025. • Huiting Jia, Simone Brixius-Anderko. Unraveling the role of CYP4F11 in lung cancer: Indications for a cross talk with fatty acid desaturase 2. Poster presentation at ASPET, Portland, Apr 2025 • Huiting Jia, Simone Brixius-Anderko. Unraveling the role of CYP4F11 in lung cancer: Indications for a cross talk with fatty acid desaturase 2. Podium presentation at PSRS, Pittsburgh, Feb 2025. Recipient of the Best Podium Presentation Award. • Huiting Jia, Bjoern Brixius, Simone Brixius-Anderko. Potential of CYP4F11 as a Therapeutic Target in Lung Cancer. Poster presentation at the Molecular Biophysics and Structural Biology (MBSB) Symposium, Pittsburgh, May 2024. • Huiting Jia, Bjoern Brixius, Simone Brixius-Anderko. Fatty Acid Metabolizing Cytochrome P450 4F11 as a Novel Drug Target for Lung Cancer Treatment. Poster presentation at ASPET, Arlington, May 2024. • Huiting Jia, Sutapa Ray, Bjoern Brixius, Simone Brixius-Anderko, Deciphering the role of fatty acid metabolizing CYP4F11 in lung cancer and its potential as a drug target. Poster presentation at ASPET, St. Louis, May 2023. • Huiting Jia, Sutapa Ray, Bjoern Brixius, Simone Brixius-Anderko, Deciphering the role of fatty acid metabolizing CYP4F11 in lung cancer and its potential as a drug target. Poster presentation at the Great Lakes Drug Metabolism Discussion Group (GLDMD), Michigan, May 2023.
Advisor
Dr. Simone Brixius-Anderko
