Wenchen Zhao

An Approach for Improving the Detection and Quantitation of Buprenorphine and Its Metabolites in Maternal and Neonatal Hair OY Alshogran, W Zhao, EE Krans, S Caritis, IH Shaik, R Venkataramanan Therapeutic Drug Monitoring 47 (3), 413-420 2025 POPULATION PHARMACOKINETIC ANALYSIS TO OPTIMIZE THE DOSING REGIMEN OF 17-OHPC FOR PREVENTION OF PRETERM BIRTH P Dodeja, M Gopalakrishnan, S Sharma, W Zhao, S Caritis, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 117, S66-S67 2025 NCOA4 linked to endothelial cell ferritinophagy and ferroptosis: a key regulator aggravate aortic endothelial inflammation and atherosclerosis L Zhu, Z Liu, J Liu, Z Li, Y Bao, X Sun, W Zhao, A Zhou, H Wu Redox Biology 79, 103465 29 2025 The dosing regimen for 17-hydroxyprogesterone caproate was suboptimal: lessons for future pharmacotherapy for pregnant women SN Caritis, P Dodeja, S Sharma, W Zhao, R Venkataramanan American Journal of Obstetrics and Gynecology 232 (1), 132. e1-132. e11 2 2025 Vaginal administration of 17-alpha hydroxyprogesterone caproate appears to be safe in non-pregnant female rats and rabbits IH Shaik, N Chaphekar, V Vasudevan, A Alshabi, A AlOwaifeer, W Zhao, ... Xenobiotica 54 (10), 821-830 2 2024 Metabolomic and biochemical changes in the plasma and liver of toxic milk mice model of Wilson disease Q Liu, X Wu, C Liu, N Wang, F Yin, H Wu, S Cao, W Zhao, H Wu, A Zhou Journal of Pharmaceutical and Biomedical Analysis, 116255 1 2024 Simplified processing and rapid quantification of buprenorphine, norbuprenorphine, and their conjugated metabolites in human plasma using UPLC–MS/MS: Assessment of … W Zhao, OY Alshogran, H Zhang, A Joshi, EE Krans, S Caritis, IH Shaik, ... Journal of Mass Spectrometry 59 (4), e5015 4 2024 Simultaneous quantitation of ketamine, norketamine and dehydronorketamine in human milk using a novel ultra high-performance liquid chromatography-mass spectrometry (UPLC-MS/MS … A Shahane, W Zhao, N Pakalapati, OY Alshogran, SN Caritis, G Lim, ... Journal of pharmaceutical and biomedical analysis 234, 115502 5 2023 Protective effect of curcumin on hepatolenticular degeneration through copper excretion and inhibition of ferroptosis X Sun, X Zhang, H Yan, H Wu, S Cao, W Zhao, T Dong, A Zhou Phytomedicine 113, 154539 36 2023 Effect of formulation and route of administration on the distribution of 17-hydroxyprogesterone caproate in rats IH Shaik, N Chaphekar, V Vasudevan, A Alshabi, JR Bastian, W Zhao, ... Xenobiotica 53 (3), 193-200 2 2023 Assessment of glomerular filtration and tubular secretion in baboons with life‐supporting pig kidney grafts C Hansen‐Estruch, MH Bikhet, IH Shaik, V Vasudevan, W Zhao, M Javed, ... Xenotransplantation 30 (2), e12795 13 2023 Protective Mechanism of Gandou Decoction in a Copper-Laden Hepatolenticular Degeneration Model: In Vitro Pharmacology and Cell Metabolomics F Yin, M Nian, N Wang, H Wu, H Wu, W Zhao, S Cao, P Wu, A Zhou Frontiers in Pharmacology 13, 848897 14 2022 Liver and urine metabolomics reveal the protective effect of Gandou decoction in copper-laden Hepatolenticular degeneration model rats AZ Rujing Xu, Juan Liang, Meimei Cheng, Hongfei Wu, Huan Wu, Shijian Cao ... J Chromatogr B 1179 (122844) 12 2021 A pilot study of oral treprostinil pharmacogenomics and treatment persistence in patients with pulmonary arterial hypertension JC Coons, K Crisamore, S Adams, A Modany, MA Simon, W Zhao, ... Therapeutic Advances in Respiratory Disease 15, 17534666211013688 5 2021 A PILOT PHARMACOKINETIC EVALUATION OF SUBLINGUAL BUPRENORPHINE IN PATIENTS WITH OPIOID USE DISORDER IN PUERTO RICO. D Santiago, V Mangas, K Melin, J Duconge, W Zhao, R Venkataramanan CLINICAL PHARMACOLOGY & THERAPEUTICS 109, S65-S65 2021 Pharmacokinetic characterization and external evaluation of a quantitative framework of sublingual buprenorphine in patients with an opioid disorder in Puerto Rico D Santiago, V Mangas-Sanjuan, K Melin, J Duconge, W Zhao, ... Pharmaceutics 12 (12), 1226 6 2020 Evaluation of renal anionic secretion following living-donor and deceased-donor renal transplantation: a clinical pharmacokinetic study of cefoxitin microdosing HV Kalluri, P Sood, W Zhao, PS Randhawa, AD Tevar, S Hariharan, ... Transplantation direct 6 (6), e561 2 2020 Pregnancy alters CYP-and UGT-mediated metabolism of buprenorphine H Zhang, JR Bastian, W Zhao, H Chen, IH Shaik, N Chaphekar, SN Caritis, ... Therapeutic drug monitoring 42 (2), 264-270 49 2020 Correction to “Targeted Delivery of Doxorubicin by Folic Acid-Decorated Dual Functional Nanocarrier” J Lu, W Zhao, Y Huang, H Liu, R Marquez, RB Gibbs, J Li, ... Molecular Pharmaceutics 16 (9), 4087-4087 2019 Creatine based polymer for codelivery of bioengineered MicroRNA and chemodrugs against breast cancer lung metastasis J Xu, J Sun, PY Ho, Z Luo, W Ma, W Zhao, SB Rathod, CA Fernandez, ... Biomaterials 210, 25-40 51 2019 Pharmacokinetics of Intravenous Isavuconazole in Solid Organ Transplant Recipients MHN Xuemei Wu , Cornelius J Clancy , Ryan M Rivosecchi Wenchen Zhao, Ryan K ... Antimicrob. Agents Chemother 46 2018 Novel Glucosylceramide Synthase Inhibitor Based Prodrug Copolymer Micelles for Delivery of Anticancer Agents J Xu, W Zhao, J Sun, Y Huang, P Wang, R Venkataramanan, D Yang, ... Journal of Controlled Release 288, 212-216 22 2018 Serum Isavuconazole (ISA) troughs in adult solid organ transplant patients (SOT pts) receiving prophylaxis R Rivosecchi, CJ Clancy, R Marini, X Wu, W Zhao, L Clarke, R Shields, ... MEDICAL MYCOLOGY 56, S25-S25 2018 Mycophenolic acid for topical immunosuppression in vascularized composite allotransplantation: optimizing formulation and preliminary evaluation of bioavailability and … FG Feturi, M Weinstock, W Zhao, W Zhang, JT Schnider, VE Erbas, ... Frontiers in surgery 5, 20 23 2018 Erratum for Hoberman et al.,“Reduced-Concentration Clavulanate for Young Children with Acute Otitis Media” A Hoberman, JL Paradise, HE Rockette, JH Jeong, DH Kearney, ... Antimicrobial Agents and Chemotherapy 62 (1), e02110-17 2018 An elastomeric polymer matrix, PEUU-Tac, delivers bioactive tacrolimus transdurally to the CNS in rat Y van der Merwe, AE Faust, I Conner, X Gu, F Feturi, W Zhao, B Leonard, ... EBioMedicine 26, 47-59 15 2017 The association among cytochrome P450 3A, progesterone receptor polymorphisms, plasma 17-alpha hydroxyprogesterone caproate concentrations, and spontaneous preterm birth ML Bustos, SN Caritis, KA Jablonski, UM Reddy, Y Sorokin, T Manuck, ... American journal of obstetrics and gynecology 217 (3), 369. e1-369. e9 17 2017 Doxorubicin delivered by a redox-responsive dasatinib-containing polymeric prodrug carrier for combination therapy J Sun, Y Liu, Y Chen, W Zhao, Q Zhai, S Rathod, Y Huang, S Tang, ... Journal of Controlled Release 258, 43-55 121 2017 Cytochrome P450 3A Function after Small Bowel and Modified Multivisceral Transplantation in Human JJ Bonner, K Md-Miah, RJ Cruz, W Zhao, G Costa, MH Nguyen, ... Transplantation 101 (6S2), S78 2017 Therapeutic Concentrations of Voriconazole Can Be Achieved after Oral Administration to Patients with Ultra-Short Bowel Syndrome JJ Bonner, V Pillai, K Md-Miah, RJ Cruz, W Zhao, S Zhang, G Costa, ... Transplantation 101 (6S2), S120 2017 Programmable co-delivery of the immune checkpoint inhibitor NLG919 and chemotherapeutic doxorubicin via a redox-responsive immunostimulatory polymeric prodrug carrier J Sun, Y Chen, Y Huang, W Zhao, Y Liu, R Venkataramanan, B Lu, S Li Acta Pharmacologica Sinica 38 (6), 823-834 79 2017 Reduced-Concentration Clavulanate for Young Children with Acute Otitis Media SN Hoberman A1, Paradise JL2, Rockette HE2, Jeong JH2, Kearney DH2 ... Antimicrob Agents Chemother 12 2017 Validation of HPLC-UV Method for Analysis of 4-Pyridoxic Acid in Human Urine SM Mohammad Shawaqfeh, Wenchen Zhao International Journal of Medical Research & Health Sciences 6 (12), 100-104 1* 2017 A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties AM Clark, SE Wheeler, CL Young, L Stockdale, JS Neiman, W Zhao, ... Lab on a Chip 17 (1), 156-168 91 2017 An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy Yichao Chen, Rui Xia, Yixian Huang, Wenchen Zhao, Jiang Li, Xiaolan Zhang ... Nature Communications, 1-12 192* 2016 A prodrug micellar carrier assembled from polymers with pendant farnesyl thiosalicylic acid moieties for improved delivery of paclitaxel J Sun, Y Chen, K Li, Y Huang, X Fu, X Zhang, W Zhao, Y Wei, L Xu, ... Acta biomaterialia 43, 282-291 45 2016 Pharmacokinetics of Posaconazole Suspension in Lung Transplant Recipients With and Without Cystic Fibrosis SRK Zhang H Nguyen MH, Clancy CJ, Joshi R, Zhao W, Ensor C, Venkataramanan R Antimicrob. Agents Chemother 59 (4) 18* 2016 Pharmacokinetics of Posaconazole Suspension in Lung Transplant 1 Recipients With and Without Cystic Fibrosis 2 H Zhang, MH Nguyen, CJ Clancy, R Joshi, W Zhao, C Ensor, ... 2016 Effective co-delivery of doxorubicin and dasatinib using a PEG-Fmoc nanocarrier for combination cancer chemotherapy P Zhang, J Li, M Ghazwani, W Zhao, Y Huang, X Zhang, ... Biomaterials 67, 104-114 141 2015 An improved D-α-tocopherol-based nanocarrier for targeted delivery of doxorubicin with reversal of multidrug resistance J Lu, W Zhao, H Liu, R Marquez, Y Huang, Y Zhang, J Li, W Xie, ... Journal of controlled release 196, 272-286 64 2014 Targeted delivery of anticancer agents via a dual function nanocarrier with an interfacial drug-interactive motif X Zhang, Y Huang, W Zhao, H Liu, R Marquez, J Lu, P Zhang, Y Zhang, ... Biomacromolecules 15 (11), 4326-4335 35 2014 Targeted delivery of doxorubicin by folic acid-decorated dual functional nanocarrier J Lu, W Zhao, Y Huang, H Liu, R Marquez, RB Gibbs, J Li, ... Molecular pharmaceutics 11 (11), 4164-4178 135 2014 Fmoc-Conjugated PEG-Vitamin E2 Micelles for Tumor-Targeted Delivery of Paclitaxel: Enhanced Drug-Carrier Interaction and Loading Capacity Y Zhang, Y Huang, W Zhao, J Lu, P Zhang, X Zhang, J Li, X Gao, ... The AAPS journal 16 (6), 1282-1291 23 2014 PEG-farnesyl thiosalicylic acid telodendrimer micelles as an improved formulation for targeted delivery of paclitaxel X Zhang, Y Huang, W Zhao, Y Chen, P Zhang, J Li, R Venkataramanan, ... Molecular pharmaceutics 11 (8), 2807-2814 46 2014 A PEG-Fmoc conjugate as a nanocarrier for paclitaxel P Zhang, Y Huang, H Liu, RT Marquez, J Lu, W Zhao, X Zhang, X Gao, ... Biomaterials 35 (25), 7146-7156 76 2014 Quality assessment of compounded 17-hydroxyprogesterone caproate J Chang, Y Zhao, W Zhao, R Venkataramanan, SN Caritis, ... American journal of obstetrics and gynecology 210 (1), 47. e1-47. e7 16 2014 Design and evaluation of a PEGylated lipopeptide equipped with drug-interactive motifs as an improved drug carrier P Zhang, J Lu, Y Huang, W Zhao, Y Zhang, X Zhang, J Li, ... The AAPS journal 16 (1), 114-124 40 2014 Identification of Three Novel Natural Product Compounds that Activate PXR and CAR and Inhibit Inflammation: Kittayaruksakul et al. S Kittayaruksakul, W Zhao, M Xu, S Ren, J Lu, J Wang, M Downes, ... Pharmaceutical research 30 (9), 2199-2208 30 2013 Design and characterization of PEG-derivatized vitamin E as a nanomicellar formulation for delivery of paclitaxel J Lu, Y Huang, W Zhao, Y Chen, J Li, X Gao, R Venkataramanan, S Li Molecular pharmaceutics 10 (8), 2880-2890 78 2013 New potential cell source for hepatocyte transplantation: discarded livers from metabolic disease liver transplants R Gramignoli, V Tahan, K Dorko, KJ Skvorak, MC Hansel, W Zhao, ... Stem cell research 11 (1), 563-573 74 2013 PEG-farnesylthiosalicylate conjugate as a nanomicellar carrier for delivery of paclitaxel X Zhang, J Lu, Y Huang, W Zhao, Y Chen, J Li, X Gao, ... Bioconjugate chemistry 24 (3), 464-472 72 2013 PEG-derivatized embelin as a nanomicellar carrier for delivery of paclitaxel to breast and prostate cancers J Lu, Y Huang, W Zhao, RT Marquez, X Meng, J Li, X Gao, ... Biomaterials 34 (5), 1591-1600 133 2013 Progesterone and preterm birth prevention: translating clinical trials data into clinical practice (vol 206, pg 376, 2012) CD Cuppett, Y Zhao, S Caritis, S Zhang, W Zhao, R Venkataramanan AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 208 (1) 2013 Development and application of purified tissue dissociation enzyme mixtures for human hepatocyte isolation SSC Gramignoli R1, Green ML, Tahan V, Dorko K, Skvorak KJ, Marongiu F, Z(h ... cell transplantation 21 (6), 1245-1260 96 2012 PEG-derivatized embelin as a dual functional carrier for the delivery of paclitaxel Y Huang, J Lu, X Gao, J Li, W Zhao, M Sun, DB Stolz, R Venkataramanan, ... Bioconjugate chemistry 23 (7), 1443-1451 84 2012 Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice JA Morgan, SB Cheepala, Y Wang, G Neale, M Adachi, D Nachagari, ... Journal of Biological Chemistry 287 (18), 14456-14466 49 2012 Lower Bioavailability and Shorter Half-Life of Voriconazole in Pediatric BMT Patients K Han, R Windreich, R Venkataramanan, J Rivett, W Zhao, RK Goyal Biology of Blood and Marrow Transplantation 18 (2), S320-S321 2012 Effects of endogenous steroids on 17alpha-hydroxyprogesterone caproate (17-OHPC) metabolism C Cuppett, W Zhao, S Caritis, R Venkataramanan American Journal of Obstetrics and Gynecology 204 (1), S29 19* 2011 Hepatic ischemia-reperfusion injury impairs drug metabolism and treprostinil, a prostacyclin analog, improves the functional capacity of the liver graft post-transplantation N Ghonem, W Zhao, S Zhang, N Murase, J Yoshida, DB Stolz, A Humar, ... Drug Metabolism Reviews 42, 81-82 1 2010 氮杂多环光致发光分子用于食品中 脂肪胺的分析及质谱鉴定(Application of Nitrogen Heterocyclic Photoluminescence Molecule for the Determination of Aliphatic Amines in Food with … 刘凌君, 赵文臣, 索有瑞, 尤进茂(Lingjun Liu, Wenchen Zhao, Yourui SuoJinmao You) Journal of Instrumental Analysis 27 (9), 942~ 946 1* 2008 2-( 11H-苯[ a]咔唑)乙基氯甲酸酯柱前 衍生化用于氨基酸的高效液相色谱分析(Application of 2-(11H-benzo[a]carbazol-11-yl) Ethyl Carbonochloridate as a Precolumn Derivatization … 赵文臣, 刘凌君, 赵先恩, 丁晨旭, 索有瑞, 尤进茂(Wenchen Zhao, Lingjun Liu ... Chinese Journal of Analytical Chemistry 36 (8), 1071~ 1076 3* 2008 Application of 2-(11H-benzo[a]carbazol-11-yl) Ethyl Carbonochloridate as a Precolumn Derivatization Reagent of Amino Acid by High Performance Liquid Chromatography with … ZHAO Wen-Chen, LIU Ling-Jun, ZHAO Xian-En, DING Chen-Xu, SUO You-Rui, YOU ... Chin J Anal Chem 36 (8), 1071–1076 8 2008 2-(11H-苯[ a]咔唑)-乙基氯甲酸酯(BCEC-Cl) 合成与结构表征(The Synthesis and Structure Characterization of FluoresocenceReagent 2-(11H-benzo[ a] carbazol-11-yl)EthylChloroformate) 刘凌君, 赵文臣 尤进茂(Lingju Liu, Wenchen ZhaoJinmao You) Journal　of　Qufu　Normal　Universit 34 (3), 76-78 2* 2008 CE determination of 2-(9-carbazole) ethyl chloroformate-labeled oligopeptides C Ding, X Sun, X Zhao, W Zhao, Y Li, H Wang, Y Suo, J You Chromatographia 67 (3), 245-251 2 2008 氮杂环荧光试剂2-( 11H-苯[ a]咔唑)乙基氯甲酸酯 对胺类化合物标记及质谱鉴定(Mass Spectrometric Identification of Aliphatic Amines Using 2-(11H-benzo[a]carbazol-11-yl) Ethyl … 赵文臣, 刘凌君, 朱芳, 赵先恩, 刘素娟, 索有瑞, 尤进茂(Wenchen Zhao, Lingjun ... Chinese Journal of Analytical Chemistry 35 (9), 1251~ 1256 3* 2007 Mass Spectrometric Identification of Aliphatic Amines Using 2-(11H-benzo[a]carbazol-11-yl) Ethyl Chloroformate as Fluorescence Labeling Reagent Zhao Wen-Chen, Liu Ling-Jun, Zhu Fang, Zhao Xian-En, Liu Su-Juan, Suo You ... Chin J Anal Chem 35 (9), 1251–1256 3 2007 Determination of amines using 2-(11H-benzo [a] carbazol-11-yl) ethyl chloroformate (BCEC-Cl) as labeling reagent by HPLC with fluorescence detection and identification with APCI/MS J You, W Zhao, L Liu, X Zhao, Y Suo, H Wang, Y Li, C Ding Talanta 72 (3), 914-925 32 2007 高效液相色谱-质谱分离鉴定荧光试剂标记的脂肪酸(Determination of Free Fatty Acids by High Performance Liquid Chromatography with Fluorescence Detection and Identification with … 朱芳, 赵文臣, 赵先恩, 索有瑞, 刘素娟尤进茂(Fang Zhu, Wenchen Zhao, Xian'en ... Chinese Journal of Analytical Chemistry 35 (4), 489~ 494 6* 2007 Determination of Free Fatty Acids by High Performance Liquid Chromatography with Fluorescence Detection and Identification with Mass Spectrometry Zhu Fang, Zhao Wen-Chen, Zhao Xian-En, Suo You-Rui, Liu Su-Juan, You Jin-Mao Chin J Anal Chem 35 (4), 489–494 9 2007 Study of a new derivatizing reagent that improves the analysis of amino acids by HPLC with fluorescence detection: application to hydrolyzed rape bee pollen J You, L Liu, W Zhao, X Zhao, Y Suo, H Wang, Y Li Analytical and bioanalytical chemistry 387 (8), 2705-2718 44 2007 Analysis of saturated free fatty acids from pollen by HPLC with fluorescence detection J You, F Zhu, W Zhao, X Zhao, Y Suo, S Liu European journal of lipid science and technology 109 (3), 225-236 18 2007 [Synthesis of 1-[2-(p-toluenesulfonate) ethyl]-2-phenylimidazole [4, 5-f] 9, 10-phenanthrene and its application for analysis of long-chain fatty acids]. X Zhao, Y Suo, C Ding, F Zhu, J Sun, W Zhao, X Sun, J You Se pu= Chinese Journal of Chromatography 24 (5), 456-461 4 2006 Metabolomics and Pathological Changes in the Plasma and Liver of Toxic Milk Mice Modeling Wilson Disease Q Liu, X Wu, C Liu, N Wang, F Yin, H Wu, S Cao, W Zhao, H Wu, A Zhou Available at SSRN 4743930 Articles 1–73