Office: 638 Salk Hall

Phone: 412-624-5150

Fax: 412-624-1850

Email: Kane-Gill@pitt.edu

orcidpubmed

Sandra L. Kane-Gill, PharmD, MS, FCCM, FCCP, is Associate Professor of Pharmacy and Therapeutics at the University of Pittsburgh School of Pharmacy in Pittsburgh, Pennsylvania. She has secondary appointments in the School of Medicine in the Clinical Translational Science Institute, Deparment of Critical Care Medicine and the Department of Biomedical Informatics. She also serves as Associate Professor for the Center for Critical Care Nephrology and Center for Pharmaceutical Policy and Prescribing. In addition to her academic appointments, Dr. Kane-Gill is Critical Care Medication Safety Pharmacist at the University of Pittsburgh Medical Center in the Department of Pharmacy.

Dr. Kane-Gill received her Bachelor of Science degree in pharmacy from Wayne State University in Detroit, Michigan. She completed a pharmacy practice residency accredited by the American Society of Health-System Pharmacists at West Virginia University Hospital in Morgantown, West Virginia, and earned a Doctorate of Pharmacy degree from the University of Toledo in Toledo, Ohio. Dr. Kane-Gill then pursued her Master of Science degree in Pharmacy Administration with emphasis on Pharmacoeconomics and Health Outcomes at The Ohio State University in Columbus, Ohio and she completed a critical care fellowship at The Ohio State University.

Dr. Kane-Gill’s interests focus on health service research, including the assessment of economic, clinical, and quality outcomes for critically ill patients. Her goal is to identify effective approaches for the detection, prevention, and management of medication errors and adverse drug events as to improve quality of care and patient safety. Dr. Kane-Gill has served as Principal Investigator and Co-Investigator on several funded research grants in this area of study.

Most recently, she received an AHRQ R18 grant entitled "Transforming the Medication Regimen Review Process of High-Risk Drugs Using a Patient-Centered Telemedicine-Based Approach to Prevent Adverse Drug Events in the Nursing Home" (R18HS02420-01). Her work has been presented at several professional meetings, and she has published approximately 140 articles and book chapters related to critical care and patient safety. Her endeavors include editing published books on the use of high-risk intravenous medications in special patient populations and drug induced complications in critically ill patients. She is on the editorial board for Critical Care Medicine, Annals of Pharmacotherapy and Hospital Pharmacy (critical care column).

Dr. Kane-Gill is an active member of the American College of Clinical Pharmacy (ACCP), and Society of Critical Care Medicine (SCCM). She holds the elected position of member-at-large seat for the Society of Critical Care Medicine (SCCM) Council, which is the decision-making body regarding the governance of SCCM. At the 2011 Annual Meeting of ACCP, Dr. Kane-Gill received the Critical Care Practice and Research Network (PRN) Research Award and in 2013 received the Critical Care Achievement Award. At the 2015 SCCM meeting she was recognized for her contributions in medication safety error prevention with the Clinical Pharmacy and Pharmacology Section Technology Patient Safety Award. She was honored with the 2016 American Society of Health-System Pharmacists (ASHP) Preceptor Pharmacy Residency Excellence Award. A testament from her trainees and colleagues is provided http://ow.ly/S7O1306PMoO. She is a fellow in the American College of Critical Care Medicine and the American College of Clinical Pharmacy.

Evaluating the economic, clinical, and humanistic factors of drug therapy decision making for critically ill patients.

Kane-Gill SL, MacLasco A, Saul MI, Politz Smith T, Kloet M, Kim C, Anthes A, Smithburger PL, Seybert AL. Use of text searching for triggers words in medical records to identify adverse drug reactions within an ICU discharge summary. Appl Clin Inform 2016;7:660-71.

Sutherland SM, Chawla LS, Kane-Gill SL, Hsu RK, Kramer AA, Goldstein SL, Kellum JA, Ronco C, Bagshaw SM for the 15th ADQI Consensus Group. Utilizing the electronic health record to predict AKI risk and outcomes: Workgroup statements from the 15th ADQI consensus conference.Can J Kidney Health Dis 2016;3:11.

Liput S, Kane-Gill SL, Seybert AL, Smithburger PL. Attitudes and perceptions of healthcare providers and family members towards family involvement in active patient care in the intensive care unit. Crit Care Med 2016;44:1191-7.

Rivosecchi RM, Kane-Gill SL, Svec S, Campbell S, Smithburger PL. Giving your patients M.O.R.E.: The implementation of a non-pharmacologic protocol to prevent intensive care delirium. J Crit Care 2015; 31:206-11.

Buckley MS, Park AS, Anderson CS, Barletta JF, Gerkin R, O’Malley, Wicks LM, Kane-Gill SL. Impact of a clinical pharmacist stress ulcer prophylaxis management program on inappropriate use in hospitalized patients. Am J Med 2015;128:905-913.

Smithburger PL, Buckley MS, Lat I, Culver MA, Handler SM, Sokol S, Kane-Gill SL. A multicenter evaluation of off-label use and associated adverse drug reactions in adult medical intensive care units. Crit Care Med 2015; 43:1612-1621.

DiPoto JP, Buckley MS, Kane-Gill SL. Evaluation of an automated surveillance system using trigger alerts to prevent adverse drug events in the intensive care unit and general ward. Drug Saf 2015;83:311-7.

Kane-Gill SL, Smithburger PL, Williams EA, Felton MA, Wang N, Seybert AL. Published cases of adverse drug reactions: Has the quality of reporting improved over time? Ther Adv Drug Saf 2015;6:38-44.

Rivosecchi RM, Smithburger PL, Svec SM, Campbell S, Kane-Gill SL. The effect of non-pharmacologic interventions to prevent the development of delirium: An evidence based systematic review. Crit Care Nurse 2015;35:39-49.

Kane-Gill SL, Sileanu F, Murugan R, Trietley G, Handler SM, Kellum JA. Risk factors for acute kidney injury in older adults with critical illness: A retrospective cohort study. Am J Kidney Dis 2015; 85:860-9.

Benedict N, Felbinger M, Anthes A, Altawalbeh S, Ridenour TA, Kane-Gill S. Correlation of patient reported outcomes of sedation and sedation assessment scores in critically ill patients. J Crit Care 2014; 29:1132.e5-9.

Kane-Gill SL, Rubin E, Smithburger PL, Buckley MS, Dasta JF. The cost of opioid related adverse drug events. J Pain Palliat Care Pharmacother 2014; 28:282-93.

Kane-Gill SL, Leblanc JL, Dasta JF, Devabhakthuni S for the Critical Care Pharmacotherapy Trials Network (CCPTN). A multicenter study of the point prevalence of drug-induced hypotension in the ICU. Crit Care Med 2014;42:2197-2203.

Buckley MS, Kane-Gill SL, Patel SA. Clinical and economic evaluation of an evidence-based institutional epoetin-utilization management program. Clin Ther 2013;35:294-302.

Anthes, AM, Harinstein LM, Smithburger PL, Seybert AL, Kane-Gill SL. Improving adverse drug event detection in critically ill patients through screening intensive care unit transfer summaries. Pharmacoepidemiol Drug Saf 2013; 22:510-16.

Kane-Gill SL, Forsberg EA, Verrico MM, Handler SM.Comparison of three pharmacovigilance algorighms in the ICU setting: a retrospective and prospective evaluation of ADRs. Drug Saf 2012;35:645-53.

Harinstein LM, Kane-Gill SL, Smithburger PL, Culley CM, Reddy VK, Seybert AL. Use of a laboratory-drug combination alert to detect drug-induced thrombocytopenia in critically ill patients. J Crit Care 2012;27:242-249.

Kane-Gill SL, Cagle WE, Stockwell D. Active patient safety surveillance systems used to prevent ADEs in the ICU. In: Papadopoulos J, Cooper B, Kane-Gill SL, Mallow-Corbett S, Barletta J.(editors) Drug induced complications in critically ill patients: a guide for recognition and treatment. 2012:347-358.

Kane-Gill SL, Jacobi J, Rothschild JR. Adverse drug events in the ICU: risk factors, impact and role of team care. Crit Care Med 2010;suppl:s83-89

Stockwell D and Kane-Gill SL. Developing a patient safety surveillance system to prevent adverse drug events in the ICU. Crit Care Med 2010;(suppl):s117-25.

Kane-Gill SL, Van Den Bos J, Handler SM. A comparison of adverse drug reactions in ambulatory care and hospital settings using a large database. Ann Pharmacother 2010;44:1054-1060.

Ford DG, Seybert AL, Smithburger PL, Kobulinsky L, Samosky J, Kane-Gill SL. Impact of simulation-based learning on medication error rates in critically ill patients. Intens Care Med 2010;36:1526-1531.

Kane-Gill SL and Buckley MS. In: Richardson M, Chant C, Cheng JWM, Chessman KH, Hemstreet Hume AL, BA e, et al, eds. Pharmacotherapy Self-Assessment Program (PSAP), 7th ed. Safe Drug Use in the Critically Ill Patients. Lenexa, KS: American College of Clinical Pharmacy, 2010:145-159.

Kane-Gill SL, Kowiatek JG, Weber RJ. A comparison of voluntarily reported medication errors in intensive care and general care units. Qual Saf Health Care. 2010; 19:55-59.

Dasta JF, Kane-Gill SL, Pencina M, Shehabi, Y, Bokesch P, Riker R. A cost-minimization analysis of dexmedetomidine compared to midazolam for long-term sedation in the intensive care unit. Crit Care Med, 2010;38(2): 497-503.

Kane-Gill SL, Bellamy CJ, Verrico MM, Saul MI, Handler SM, Weber RJ. Evaluating the positive predictive values of antidote signals to detect potential adverse drug reactions (ADRs) in the medical intensive care unit (ICU). Pharmacoepidemiol Drug Saf 2009;18:1185-1191.

Kane-Gill SL, Rea RS, Verrico P, Weber RJ. ADE rates for high cost and frequently used drugs in the ICU: Redirecting pharmacist’s time toward ADE prevention efforts. Am J Health Syst Pharm 2006;63:1876-1881.

Kane-Gill SL, Devlin JW. Adverse drug event reporting in the intensive care unit: a survey of current practices. Ann Pharmacother 2006;40:1267-1273.

Kane-Gill SL, Dasta JF, Schneider PJ, Cook CH. Monitoring abnormal laboratory values as antecedents to drug induced injury. J Trauma 2005; 59:1457-1462.

Kane-Gill SL, Kirisci L, Pathak DS. Are the Naranjo criteria reliable and valid for determination of adverse drug reactions in the intensive care unit? Ann Pharmacother 2005; 39: 1823-1827.

2016 ASHP Residency Excellence Award- Preceptor
2016 ASHP Award for Innovation in Pharmacy Practice for outstanding contribution to the biomedical literature as a co-author on “Impact of a Clinical Pharmacist Acid Suppression
Therapy Management Program on Inappropriate Use in Intensive Care Unit and General Ward Patients” and published in Am J Med
2015 Patient and Family Support Specialty Award for the top-scoring poster at SCCM Congress in Phoenix, Az.
2015 SCCM, Clinical Pharmacy and Pharmacology Section Patient Safety Technology Award* for using an automated trigger alert system to identify ADEs
in 4 institutions in the Banner Good Samaritan Medical Center, Phoenix, AZ.
2015 SCCM, Clinical Pharmacy and Pharmacology Section Medication Safety Award for evaluating off-label drug use as a risk for ADEs in the ICU.
2014 ASHP Best Practice Award for assistance with the project “Impact of a Clinical Pharmacist Acid Suppression Therapy Management Program on
Inappropriate Use in Intensive Care Unit and General Ward Patients” at Banner Good Samaritan Medical Center in Phoenix, Az.
2014 ACCP- Mentored the Best Student Poster Award "Characterization of delirium in a medical ICU that emphasizes frequent delirium screening at a
tertiary, academic medical center", Austin, Texas
2014 Pitt Innovation Challenge (PiNCH) Finalist for “MyKidney” App and Peoples Choice Award for Video
2013 ACCP Critical Care PRN Achievement Award
2013 SCCM, Clinical Pharmacy and Pharmacology Section Medication Safety Award for evaluating the impact of transfer summaries as part of an active
surveillance system for the detection of ADEs in the ICU
2012 SCCM, CPP Section Patient Safety Technology Award for using simulation-based learning to reduce medication errors in critically ill patients.
2012 SCCM, CPP Section Medication Safety Award for evaluating the impact of pharmacist-conducted admission medication reconciliation program
2011 ACCP Critical Care PRN Research Award
2011 SCCM Research Citation Award for “Evaluating the occurrence of QT prolongation resulting from drug-drug interactions
2010 University of Pittsburgh, Rho Chi Society, Innovation in Teaching Award
2009 Fellow, American College of Clinical Pharmacy
2008 Fellow, American College of Critical Care Medicine
2008 University of Pittsburgh, Rho Chi Society, Outstanding Scholarly Contribution Award


Recent Grants

Transforming the medication regimen review process of high-risk drugs using a patient-pentered telemedicine-based Approach to prevent adverse drug events in the nursing home. Principal Investigator. Agency for Healthcare Research and Quality. 2015-2018.

"MyKidney" App Development. Co-Investigator. Clinical & Translational Science Institute, University of Pittsburgh. 2015

Enhancing the detection and management of adverse drug events in the nursing home. Co-investigator. Agency for Healthcare Research and Quality, 2010-2014.

Clinical quality improvement of benzodiazepine-resistant alcohol withdrawal syndrome. Co-Principal Investigator. Hospira Inc. 2012

A multicenter evaluation of off-label medication use and adverse drug events in adult intensive care unit patients. Senior Principal Investigator . ASHP Foundation 2012

Evaluating the impact of a dose range-checking alert for opioids in elderly patients requiring acute pain management. Principal Investigator Mentor. Cumberland Pharmaceuticals Resident Grant 2011

Recent Presentations

Striving for Early Detection of Drug-Associated AKI
Presented at the 45th SCCM Critical Care Congress, Orlando, FL

Decision Support- Preventing Drug Errors
Presented at the Critical Care Canada Forum (CCCF), Toronto, ON

GRADE-ing Drug Combinations Associated with AKI.
Presented at the 5th AKI Symposium, University of Pittsburgh, Pittsburgh, PA

Improving Medication Safety Strategies in the ICU: Maximizing Adverse Drug Event Surveillance with Automation
Presented at the 44th SCCM Critical Care Congress, Phoenix, AZ

Managing alert overload: Clinical decision support
Presented at the 43rd SCCM Critical Care Congress, San Francisco, CA

“Med Wreck or Med Safety”: The impact of medication reconciliation on medication errors and adverse drug events.
Presented at the 46th ASHP Midyear Clinical Meeting, Orlando, FL

Evaluating New Pharmaceutical Products at Your Health System - Efficacy, Safety and Economic Considerations in Developing Medication-use Evaluations
Presented at the 45th ASHP Midyear Clinical Meeting, Las Vegas, NV

Assessing and Managing Sedation – Incorporating the PAD Guidelines into Practice
Presented at the Downstate New York Society of Health System Pharmacists, New York, NY.

Establishing a Safety Culture in the ICU: Making Systematic Changes Using ADE Data
Presented at the 41st SCCM Critical Care Congress, Houston, Tx

Strategies for Improving the Safe Use of IV Medications in the Critical Care Setting.
Presented at the 44th ASHP Midyear Clinical Meeting, New Orleans, LA

Economic Implications of Postoperative Pain Management
Presented at the 44th ASHP Midyear Clinical Meeting, New Orleans, LA

The Great Masquerader: Recognizing ADRs in the ICU Learning Using Simulation
Presented at the ACCP 2011 Annual Meeting, Pittsburgh, PA.

Severity and Preventability of Drug-Induced Hypotension
Presented at the ACCP 2011 Annual Meeting, Pittsburgh, PA.

Transforming the medication regimen review process of high-risk drugs using a patient-pentered telemedicine-based Approach to prevent adverse drug events in the nursing home. Principal Investigator. Agency for Healthcare Research and Quality. 2015-2018.

"MyKidney" App Development. Co-Investigator. Clinical & Translational Science Institute, University of Pittsburgh. 2015

Enhancing the detection and management of adverse drug events in the nursing home. Co-investigator. Agency for Healthcare Research and Quality, 2010-2014.

Clinical quality improvement of benzodiazepine-resistant alcohol withdrawal syndrome. Co-Principal Investigator. Hospira Inc. 2012

A multicenter evaluation of off-label medication use and adverse drug events in adult intensive care unit patients. Senior Principal Investigator . ASHP Foundation 2012

Evaluating the impact of a dose range-checking alert for opioids in elderly patients requiring acute pain management. Principal Investigator Mentor. Cumberland Pharmaceuticals Resident Grant 2011