Directory Profile

Sandra L. Kane-Gill, PharmD, MS, FCCM, FCCP

Office: 303 Baum, 4B- 4, 5607 Baum Boulevard, 15206

Phone: 412-624-5150

Fax: 412-624-1850



Sandra L. Kane-Gill, PharmD, MS, FCCM, FCCP, is Professor of Pharmacy and Therapeutics at the University of Pittsburgh School of Pharmacy in Pittsburgh, Pennsylvania. She has secondary appointments in the School of Medicine in the Clinical Translational Science Institute, Department of Critical Care Medicine and the Department of Biomedical Informatics. She also serves as Professor for the Center for Critical Care Nephrology and Center for Pharmaceutical Policy and Prescribing. In addition to her academic appointments, Dr. Kane-Gill is Critical Care Medication Safety Pharmacist at the University of Pittsburgh Medical Center in the Department of Pharmacy.

Dr. Kane-Gill received her Bachelor of Science degree in pharmacy from Wayne State University in Detroit, Michigan. She completed a pharmacy practice residency accredited by the American Society of Health-System Pharmacists at West Virginia University Hospital in Morgantown, West Virginia, and earned a Doctorate of Pharmacy degree from the University of Toledo in Toledo, Ohio. Dr. Kane-Gill then pursued her Master of Science degree in Pharmacy Administration with emphasis on Pharmacoeconomics and Health Outcomes at The Ohio State University in Columbus, Ohio and she completed a critical care fellowship at The Ohio State University. Recently, Dr. Kane-Gill completed a certification program in implementation science through the CTSI online training program at the University of California, San Francisco.

Dr. Kane-Gill’s interests focus on the assessment of clinical, economic and quality outcomes for critically ill patients. Her goal is to identify effective approaches for the detection, prevention, and management of medication errors and adverse drug events as to improve quality of care and patient safety. She led several pharmacopidemiology evaluations that improved patient safety surveillance systems, prevented medication errors and adverse drug events (ADEs) and used health information technology (clinical decision support, telemedicine, simulation) to improve services. Dr. Kane-Gill has served as Principal Investigator and Co-Investigator on several funded research grants in this area of study. She received an AHRQ R18 grant entitled "Transforming the Medication Regimen Review Process of High-Risk Drugs Using a Patient-Centered Telemedicine-Based Approach to Prevent Adverse Drug Events in the Nursing Home" (R18HS02420-01).

Her work has been presented at several professional meetings, and she has published over 200 articles and book chapters related to critical care and patient safety. Her endeavors include editing published books on the use of high-risk intravenous medications in special patient populations and drug induced complications in critically ill patients. She is on the editorial board for Critical Care Medicine and Annals of Pharmacotherapy. Dr. Kane-Gill is an active member of the American College of Clinical Pharmacy (ACCP), and Society of Critical Care Medicine (SCCM). She is a faculty member of the Research and Scholarship Academy of ACCP. She holds the elected position of Treasurer on the Executive Committee for the Society of Critical Care Medicine (SCCM), which is the decision-making body regarding the governance of SCCM. She is a fellow in the American College of Critical Care Medicine and the American College of Clinical Pharmacy.

Evaluating the clinical, economic and humanistic factors of drug therapy decision making for critically ill patients.

Selections from a list of 160 peer-reviewed publications:

Kane-Gill SL, Peerapornratana W, Wong, A Groetzinger LM, Kim C, Smithburger PL, Then J, Murugan R, Kellum JA. Use of TIMP2-IGFBP7 as an AKI risk screening tool to manage patients in the real-world setting. J Crit Care 2020;57:97-101

Buckley MS, Agarwal SK, MacLaren R, Kane-Gill SL. Adverse hemodynamic events associated with concomitant dexmedetomidine and propofol for sedation in mechanically ventilated ICU patients. J Intensiv Care Med 2019; epub ahead of print.

Malinowski A, Benedict N, Ho M, Kirisci L, Kane-Gill SL. Patient reported outcomes associated with sedation and agitation intensity in the critically ill. Am J Crit Care 2020;29: 29;140-44.

Kane-Gill SL, Ostermann M, Shi J, Joyce EL, Kellum JA. Evaluating renal stress using pharmacokinetic urinary biomarker data in critically ill patients receiving vancomycin and/or piperacillin-tazobactam: A secondary analysis of the multicenter sapphire study. Drug Saf 2019; 42:1149-55.

Fitzmaurice MG, Wong A, Akerberg H, Avramovska S, Smithburger PL, Buckley MS, Kane-Gill SL. Evaluation of potential drug-drug interactions in adults in the intensive care unit: a systematic review and meta-analysis. Drug Saf 2019;42:1035-44.

Altawalbeh SM, Abu-Su’ud R, Alefan Q, Momany S, Kane-Gill SL. Evaluating intensive care unit medication charges in a teaching hospital in Jordan. Expert Rev Pharmacoecon Outcomes Res 2019;28:1-7.

Barreto EF, Rule AD, Kieske JC, Kashani KB, Hassan Murad M, Erwin P, Kane-Gill SL. Prediction of renal elimination of drugs with cystatin C versus creatinine: a systematic review. Mayo Clinic Pro 2019;94:500-14.

Benedict NJ, Wong A, Cassidy EA, Lohr BR, Pizon TF, Smithburger PL, Falcione B, Kirsci L, Kane-Gill SL. Predictors of resistant alcohol withdrawal. Drug Alcohol Depend 2018;192:303-8.

Strnad K, Shoulders BR, Smithburger PL, Kane-Gill SL. A systematic review of non-ICU and ICU pharmacy services using telepharmacay. Ann Pharmacother 2018; 52;1250-58.

Pizon AF, Lynch AJ, Benedict NJ, Yanta JH, Frisch A, Menke NB, Swartzentruber GS, King AM, Abesamis MG, Kane-Gill SL. Adjunct ketamine use in the management of severe ethanol withdrawal. Crit Care Med 2018; 46:e768-771.

Kane-Gill SL, Dasta JF, Buckley MS, Devabhakthuni S, Lui M, Cohen H, George EL, Pohlman AS, Agarwal S, Henneman EA, Bejian SM, Berneholtz S, Pepin JL, Scanlon MC, Smith BS. Clinical Practice Guideline: Safe Medication Use in the ICU. Crit Care Med 2017;45(9):e877-e915

Chawla LS, Bellomo R, Bihorac A, Goldstein SL, Siew E, Bagshaw S, Bittleman D, Cruz D, Endre Z, Fitzgerald RL, Forni L, Kane-Gill SL, Hoste E, Koyner J, Liu K, Macedo E, Mehta R, Murray P, Nadim M, Ostermann M, Palevsky P, Pannu N, Rosner M, Wald R, Zarbock A, Ronco C, Kellum JA. Acute Kidney Disease and Renal Recovery: Consensus Report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup. Nat Review Nephrol 2017;13;241-47.

2020 UPMC Quality and Safety Fair- Safety award (second place) recognizes a project that provides safe and effective care to our patients through error reduction. Project: Medication
optimization upon transition of care from the medication intensive care unit.
2019 Pennsylvania Pharmacists Association Excellence in Innovation Award recognizes a pharmacist who is involved in an innovative pharmacy practice resulting in improved patient
2019 West Virginia University Hospitals, Commitment to Pharmacy Excellence Award
2016 ASHP Residency Excellence Award- Preceptor
2016 ASHP Award for Innovation in Pharmacy Practice for outstanding contribution to the biomedical literature as a co-author on “Impact of a Clinical Pharmacist Acid Suppression
Therapy Management Program on Inappropriate Use in Intensive Care Unit and General Ward Patients” and published in Am J Med
2015 Patient and Family Support Specialty Award for the top-scoring poster at SCCM Congress in Phoenix, Az.
2015 SCCM, Clinical Pharmacy and Pharmacology Section Patient Safety Technology Award* for using an automated trigger alert system to identify ADEs
in 4 institutions in the Banner Good Samaritan Medical Center, Phoenix, AZ.
2015 SCCM, Clinical Pharmacy and Pharmacology Section Medication Safety Award for evaluating off-label drug use as a risk for ADEs in the ICU.
2014 ASHP Best Practice Award for assistance with the project “Impact of a Clinical Pharmacist Acid Suppression Therapy Management Program on
Inappropriate Use in Intensive Care Unit and General Ward Patients” at Banner Good Samaritan Medical Center in Phoenix, Az.
2014 ACCP- Mentored the Best Student Poster Award "Characterization of delirium in a medical ICU that emphasizes frequent delirium screening at a
tertiary, academic medical center", Austin, Texas
2014 Pitt Innovation Challenge (PiNCH) Finalist for “MyKidney” App and Peoples Choice Award for Video
2013 ACCP Critical Care PRN Achievement Award
2013 SCCM, Clinical Pharmacy and Pharmacology Section Medication Safety Award for evaluating the impact of transfer summaries as part of an active
surveillance system for the detection of ADEs in the ICU
2012 SCCM, CPP Section Patient Safety Technology Award for using simulation-based learning to reduce medication errors in critically ill patients.
2012 SCCM, CPP Section Medication Safety Award for evaluating the impact of pharmacist-conducted admission medication reconciliation program
2011 ACCP Critical Care PRN Research Award
2011 SCCM Research Citation Award for “Evaluating the occurrence of QT prolongation resulting from drug-drug interactions
2010 University of Pittsburgh, Rho Chi Society, Innovation in Teaching Award
2009 Fellow, American College of Clinical Pharmacy
2008 Fellow, American College of Critical Care Medicine
2008 University of Pittsburgh, Rho Chi Society, Outstanding Scholarly Contribution Award

Recent Presentations

Nephrotoxin Stewardship
National Kidney Foundation 2020 Spring Clinical Meeting, New Orleans, LA. (virtual)

More Than the Monitor: How Many Alarms Do We Face in a Day in the ICU?
49th SCCM Critical Care Congress, Orlando, FL

Use Biomarkers for Acute Kidney Injury: Applications for Prevention
49th SCCM Critical Care Congress, Orlando, FL

Preventing Drug Associated AKI: Real World Medication Management Experience
Cardio Renal Society of America at the American Society of Nephrology Kidney Week, San Diego, CA

Clinical Practice Guideline: Safe Medication Use in the ICU and Pharmacoeconomics and Safe Medication Use
47th SCCM Critical Care Congress, San Antonio, Tx.

Population Health and Telemedicine Approaches to Commonly Encountered Conditions
ACCP Annual Meeting, Seattle, WA.

Using Kidney Biomarkers for Guiding Drug Therapy and Drug Induced Kidney Injury in the ICU: Mechanisms, Susceptibility, Diagnosis, Management Strategies
AKI&CRRT 2018, San Diego, CA.

Promoting Best Practices in the ICU with Safe Medication Use Guidelines and The Impact of Novel Renal Biomarkers on Drug Therapy Use
52nd ASHP Midyear Clinical Meeting, Orlando, FL.

Enhancing Residents’ Training with Simulation: Knowledge, Assessment and Research
ASHP National Pharmacy Preceptors Conference, Washington, D.C.

Development, Feasibility and Acceptability of an Academic Detailing Intervention to Support Pharmacist-Led Deprescribing within UPMC Senior Communities. Co-investigator. Beckwith Institute 2019-2020.

Transforming the medication regimen review process of high-risk drugs using a patient-centered telemedicine-based Approach to prevent adverse drug events in the nursing home. Principal Investigator. Agency for Healthcare Research and Quality. 2015-2018.

"MyKidney" App Development. Co-Investigator. Clinical & Translational Science Institute, University of Pittsburgh. 2015

Enhancing the detection and management of adverse drug events in the nursing home. Co-investigator. Agency for Healthcare Research and Quality, 2010-2014.